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Medical Thesis Topics

MDS

100 Endodontics Thesis Topics

Academic session 2026-2027  · 100 topics

This page lists 100 endodontics thesis topics for Master of Dental Surgery postgraduate students for the 2026-2027 academic session. The topics are structured around practical dissertation questions that can be adapted to the clinical workload, imaging facilities, laboratory support, materials and records available in a dental teaching institution.

The endodontics thesis topics below cover root canal anatomy, access cavity design, cone-beam computed tomography, instrumentation, irrigation, obturation, sealers, endodontic biomaterials, retreatment, procedural errors, trauma and contemporary diagnostic methods. They include cross-sectional, observational, comparative, imaging-based, record-based and in-vitro approaches so that students can select a research question that matches their departmental resources while retaining a clearly measurable primary outcome.

Click any topic to open it in the protocol generator with the title already filled in.

  1. Evaluation of root canal morphology of permanent mandibular first molars using cone-beam computed tomography: a retrospective cross-sectional imaging study.Get protocol
  2. Comparison of root canal morphology of permanent mandibular first and second molars using cone-beam computed tomography: a comparative imaging study.Get protocol
  3. Evaluation of prevalence and configuration of a second mesiobuccal canal in permanent maxillary first molars using cone-beam computed tomography: a cross-sectional imaging study.Get protocol
  4. Comparison of prevalence of a second mesiobuccal canal in permanent maxillary first and second molars using cone-beam computed tomography: a comparative study.Get protocol
  5. Evaluation of root and canal morphology of permanent mandibular premolars using cone-beam computed tomography: a retrospective cross-sectional study.Get protocol
  6. Comparison of root canal configurations of permanent mandibular first premolars and second premolars using cone-beam computed tomography: a comparative imaging study.Get protocol
  7. Evaluation of root canal morphology of permanent maxillary premolars in an Indian population using cone-beam computed tomography: a cross-sectional study.Get protocol
  8. Prevalence and morphological characteristics of C-shaped root canals in permanent mandibular second molars using cone-beam computed tomography: an observational imaging study.Get protocol
  9. Comparison of root canal morphology between male and female patients using cone-beam computed tomography: a comparative cross-sectional study.Get protocol
  10. Bilateral symmetry of root and canal morphology of permanent molars using cone-beam computed tomography: a retrospective observational study.Get protocol
  11. Prevalence and distribution of additional roots in permanent mandibular molars using cone-beam computed tomography: a cross-sectional imaging study.Get protocol
  12. Evaluation of root canal morphology of permanent maxillary first molars according to age and sex using cone-beam computed tomography: an observational cross-sectional study.Get protocol
  13. Assessment of root dentin thickness in the danger zone of mandibular molars using cone-beam computed tomography: an imaging-based cross-sectional study.Get protocol
  14. Comparison of remaining dentin thickness after traditional and conservative endodontic access cavity preparations: an in-vitro comparative study.Get protocol
  15. Comparison of fracture resistance of teeth prepared with traditional and conservative endodontic access cavities: an in-vitro study.Get protocol
  16. Effect of different access cavity designs on detection and instrumentation of root canals in permanent molars: an in-vitro comparative study.Get protocol
  17. Comparison of accuracy of conventional radiography and cone-beam computed tomography for identifying additional root canals: a comparative imaging study.Get protocol
  18. Assessment of calcified root canals and pulp chamber changes according to age using cone-beam computed tomography: a retrospective cross-sectional study.Get protocol
  19. Evaluation of prevalence and distribution of pulp stones using cone-beam computed tomography: a cross-sectional imaging study.Get protocol
  20. Association between pulp stone occurrence and selected demographic and dental characteristics using existing radiographic records: an observational cross-sectional study.Get protocol
  21. Comparison of canal transportation and centering ability of different nickel-titanium rotary file systems in curved root canals: an in-vitro study.Get protocol
  22. Comparison of shaping ability of rotary and reciprocating nickel-titanium instrumentation systems: an in-vitro comparative study.Get protocol
  23. Evaluation of remaining dentin thickness following root canal preparation with different rotary instrumentation systems: an in-vitro study.Get protocol
  24. Comparison of apically extruded debris produced by rotary and reciprocating instrumentation systems: an in-vitro comparative study.Get protocol
  25. Comparison of apically extruded debris produced by different heat-treated nickel-titanium file systems: an in-vitro study.Get protocol
  26. Evaluation of dentinal microcrack formation after root canal preparation using different instrumentation systems: an in-vitro comparative study.Get protocol
  27. Comparison of root canal preparation time using rotary and reciprocating instrumentation systems: an in-vitro study.Get protocol
  28. Comparison of cyclic fatigue resistance of different heat-treated nickel-titanium rotary instruments: an in-vitro comparative study.Get protocol
  29. Effect of different temperatures on cyclic fatigue resistance of nickel-titanium endodontic instruments: an in-vitro study.Get protocol
  30. Comparison of torsional resistance of different nickel-titanium rotary file systems: an in-vitro comparative study.Get protocol
  31. Comparison of antimicrobial efficacy of sodium hypochlorite at different concentrations against Enterococcus faecalis in infected root canals: an in-vitro study.Get protocol
  32. Comparison of antimicrobial efficacy of sodium hypochlorite, chlorhexidine and selected alternative irrigating solutions against Enterococcus faecalis: an in-vitro comparative study.Get protocol
  33. Evaluation of smear layer removal by different final irrigation protocols using scanning electron microscopy: an in-vitro study.Get protocol
  34. Comparison of conventional syringe irrigation, sonic activation and ultrasonic activation for smear layer removal: an in-vitro comparative study.Get protocol
  35. Comparison of bacterial reduction achieved by conventional, sonic and ultrasonic irrigation activation techniques: an in-vitro study.Get protocol
  36. Effect of irrigant activation techniques on penetration of irrigating solutions into dentinal tubules: an in-vitro comparative study.Get protocol
  37. Comparison of debris removal from root canal irregularities using different irrigation activation systems: an in-vitro study.Get protocol
  38. Effect of different irrigation protocols on microhardness of root canal dentin: an in-vitro comparative study.Get protocol
  39. Comparison of fracture resistance of root-treated teeth following exposure to different irrigation protocols: an in-vitro study.Get protocol
  40. Evaluation of effectiveness of different irrigation activation methods for removal of intracanal calcium hydroxide: an in-vitro comparative study.Get protocol
  41. Comparison of sealing ability of bioceramic and epoxy resin-based root canal sealers: an in-vitro study.Get protocol
  42. Evaluation of dentinal tubule penetration of bioceramic and resin-based root canal sealers using confocal laser scanning microscopy: an in-vitro comparative study.Get protocol
  43. Comparison of push-out bond strength of different bioceramic root canal sealers to radicular dentin: an in-vitro study.Get protocol
  44. Effect of different final irrigation protocols on bond strength of bioceramic and resin-based sealers: an in-vitro comparative study.Get protocol
  45. Comparison of marginal adaptation of different root canal sealers using scanning electron microscopy: an in-vitro study.Get protocol
  46. Evaluation of voids in root canal fillings obtained with different obturation techniques using micro-computed tomography: an in-vitro comparative study.Get protocol
  47. Comparison of obturation quality achieved with single-cone and warm vertical compaction techniques: an in-vitro study.Get protocol
  48. Comparison of percentage of gutta-percha-filled area following different obturation techniques: an in-vitro comparative study.Get protocol
  49. Evaluation of apical sealing ability of different obturation techniques: an in-vitro study.Get protocol
  50. Comparison of fracture resistance of endodontically treated teeth obturated using different root canal sealers: an in-vitro comparative study.Get protocol
  51. Evaluation of solubility and dimensional stability of different commercially available bioceramic sealers: an in-vitro study.Get protocol
  52. Comparison of flow and film thickness of bioceramic and epoxy resin-based root canal sealers: an in-vitro comparative study.Get protocol
  53. Evaluation of pH and calcium ion release of different calcium silicate-based endodontic materials: an in-vitro study.Get protocol
  54. Comparison of push-out bond strength of mineral trioxide aggregate and newer calcium silicate-based materials: an in-vitro comparative study.Get protocol
  55. Evaluation of marginal adaptation of different materials used for perforation repair: an in-vitro study.Get protocol
  56. Comparison of sealing ability of different materials used for furcation perforation repair: an in-vitro comparative study.Get protocol
  57. Effect of blood contamination on bond strength of calcium silicate-based repair materials: an in-vitro study.Get protocol
  58. Comparison of colour stability of teeth after placement of different calcium silicate-based endodontic materials: an in-vitro comparative study.Get protocol
  59. Evaluation of microleakage of different materials used as intra-orifice barriers after root canal obturation: an in-vitro study.Get protocol
  60. Comparison of fracture resistance of root canal-treated teeth restored using different intra-orifice barrier materials: an in-vitro comparative study.Get protocol
  61. Comparison of efficacy of rotary and reciprocating systems for removal of gutta-percha during root canal retreatment: an in-vitro study.Get protocol
  62. Evaluation of residual filling material following retreatment with different nickel-titanium systems: an in-vitro comparative study.Get protocol
  63. Comparison of time required for root filling removal using different retreatment systems: an in-vitro study.Get protocol
  64. Effect of supplementary irrigation activation on removal of residual root filling material during retreatment: an in-vitro comparative study.Get protocol
  65. Comparison of removal efficiency of bioceramic and epoxy resin-based sealers during endodontic retreatment: an in-vitro study.Get protocol
  66. Evaluation of dentinal microcracks following root canal retreatment using different instrumentation systems: an in-vitro comparative study.Get protocol
  67. Prevalence and pattern of procedural errors during root canal treatment using postoperative radiographs: a retrospective cross-sectional study.Get protocol
  68. Comparison of procedural errors in root canal treatments performed on anterior and posterior teeth: a comparative record-based study.Get protocol
  69. Prevalence and distribution of separated endodontic instruments among previously root-treated teeth: a retrospective observational study.Get protocol
  70. Assessment of factors associated with instrument separation using existing endodontic clinical records: a cross-sectional record-based study.Get protocol
  71. Prevalence and pattern of missed canals in previously root-treated teeth evaluated using cone-beam computed tomography: a retrospective cross-sectional study.Get protocol
  72. Association between missed canals and apical periodontitis in root canal-treated teeth using cone-beam computed tomography: an observational cross-sectional study.Get protocol
  73. Comparison of periapical status of adequately and inadequately root-filled teeth using existing radiographic records: a comparative cross-sectional study.Get protocol
  74. Prevalence of vertical root fractures among endodontically treated teeth referred for cone-beam computed tomography: a retrospective imaging study.Get protocol
  75. Comparison of diagnostic accuracy of periapical radiography and cone-beam computed tomography for detection of simulated vertical root fractures: an in-vitro comparative study.Get protocol
  76. Evaluation of fracture resistance of endodontically treated teeth with different amounts of remaining coronal tooth structure: an in-vitro study.Get protocol
  77. Comparison of fracture resistance of endodontically treated posterior teeth restored with direct composite restorations and endocrowns: an in-vitro comparative study.Get protocol
  78. Effect of different ferrule configurations on fracture resistance of endodontically treated anterior teeth: an in-vitro study.Get protocol
  79. Comparison of fracture resistance of immature teeth reinforced using different intra-radicular restorative materials: an in-vitro comparative study.Get protocol
  80. Assessment of prevalence and pattern of traumatic dental injuries involving permanent anterior teeth among patients attending a dental teaching hospital: a cross-sectional study.Get protocol
  81. Prevalence and pattern of apical periodontitis among patients attending a dental teaching hospital using panoramic radiographs: a cross-sectional radiographic study.Get protocol
  82. Association between technical quality of root canal treatment and periapical status using existing radiographic records: an observational cross-sectional study.Get protocol
  83. Comparison of periapical status of single-rooted and multi-rooted endodontically treated teeth: a comparative radiographic study.Get protocol
  84. Assessment of quality of root canal fillings performed by undergraduate and postgraduate dental students using postoperative radiographs: a comparative cross-sectional study.Get protocol
  85. Evaluation of frequency and pattern of endodontically treated teeth among patients attending a tertiary dental care centre: a retrospective cross-sectional study.Get protocol
  86. Association between coronal restoration quality and periapical status of root canal-treated teeth: an observational cross-sectional study.Get protocol
  87. Comparison of periapical lesion detection using digital periapical radiography and cone-beam computed tomography: a comparative imaging study.Get protocol
  88. Comparison of accuracy of electronic apex locators and radiographic working-length determination in extracted permanent teeth: an in-vitro study.Get protocol
  89. Effect of different irrigating solutions on accuracy of electronic apex locators: an in-vitro comparative study.Get protocol
  90. Comparison of accuracy of different generations of electronic apex locators under simulated clinical conditions: an in-vitro study.Get protocol
  91. Knowledge, attitudes and practices regarding use of rubber dam isolation among dental practitioners: a cross-sectional study.Get protocol
  92. Comparison of knowledge and utilization of rubber dam isolation among general dental practitioners and postgraduate dental students: a comparative cross-sectional study.Get protocol
  93. Knowledge and practices regarding use of cone-beam computed tomography in endodontics among dental practitioners: a cross-sectional study.Get protocol
  94. Comparison of knowledge regarding endodontic irrigation protocols among general dental practitioners and postgraduate dental students: a comparative cross-sectional study.Get protocol
  95. Knowledge, attitudes and practices regarding antibiotic prescription for endodontic conditions among dental practitioners: a cross-sectional study.Get protocol
  96. Comparison of antibiotic-prescribing knowledge among undergraduate interns and postgraduate dental students for common endodontic conditions: a comparative cross-sectional study.Get protocol
  97. Knowledge and practices regarding management of endodontic emergencies among dental practitioners: an observational cross-sectional study.Get protocol
  98. Assessment of awareness and clinical decision-making regarding regenerative endodontic procedures among postgraduate dental students: a cross-sectional study.Get protocol
  99. Comparison of knowledge and attitudes regarding vital pulp therapy among general dental practitioners and endodontic postgraduate students: a comparative cross-sectional study.Get protocol
  100. Knowledge, attitudes and practices regarding contemporary endodontic technologies among dental practitioners in an Indian urban setting: a cross-sectional study.Get protocol

Choosing a Endodontics thesis topic

How should I choose a feasible Endodontics thesis topic?

Start with the cases, records, imaging facilities, laboratory methods and materials that are consistently available in your department. A feasible endodontic thesis should have a clearly defined primary outcome and should not depend on expensive equipment or rare patients unless access is already assured. Before finalizing the protocol, review recent departmental case numbers, identify the variables that can be measured reliably, and decide whether the proposed comparison groups are realistically available. A focused question with adequate numbers is usually stronger than a technically ambitious project that cannot recruit or complete its planned measurements.

Which study designs are practical for an MDS thesis in Endodontics?

Cross-sectional, comparative cross-sectional, retrospective record-based, imaging-based and in-vitro designs are often practical for an MDS dissertation because they can be completed within a defined academic period. The best design depends on the research question and available resources. Clinical prevalence or association questions generally suit cross-sectional methods, existing case records can support retrospective studies, and material or technique comparisons may suit controlled in-vitro work. The protocol should specify the sampling method, primary variable, measurement technique and statistical comparison in advance rather than selecting a design solely because it appears easy to conduct.

What should be checked before finalizing a Endodontics dissertation protocol?

Confirm that the department can provide enough eligible observations during the proposed study period and that every major variable can be measured using a standardized method. For imaging or record-based work, review a small sample of existing records to assess completeness and consistency. For in-vitro projects, verify availability of specimens, materials, equipment and the testing method before calculating the sample size. The final protocol should clearly separate the primary objective from secondary objectives, define inclusion and exclusion criteria, identify potential confounders where relevant, and use outcomes that directly answer the stated research question.

Thesis and protocol questions

How is a thesis topic different from a thesis protocol?

The topic is the title — the question a study sets out to answer, together with the population and the design. The protocol is the full document built around it: background, review of literature, aims and objectives, inclusion and exclusion criteria, sample size calculation, methodology, statistical plan, ethics considerations, consent documents and references. A topic is agreed with a guide first; the protocol is written afterwards and submitted to the institutional ethics committee.

When does a postgraduate thesis have to be submitted?

For most Indian postgraduate programmes the protocol is submitted within the first six months of joining, and the completed thesis is submitted at least six months before the final examination. Exact deadlines are set by the university, so the departmental circular for the current session takes precedence over any general timeline.

How is sample size decided for a postgraduate thesis?

Sample size follows from the primary objective, not the other way round. A prevalence study is powered from an expected proportion and an acceptable margin of error; a comparative study is powered from the expected difference between groups, the standard deviation, alpha and desired power. The figure should then be checked against the institution's actual case load for the study period, because a statistically ideal sample that cannot be recruited in the time available is not a workable plan.

Does a thesis topic need ethics committee approval?

Yes. Every postgraduate thesis involving human participants, human data or human samples requires clearance from the institutional ethics committee before data collection begins. Approval is granted on the protocol rather than on the title, and the submission usually includes the protocol, the participant information sheet and the consent form in English and in the local language.

What makes a topic realistic for a three-year postgraduate programme?

A workable topic can be completed at a single centre, with equipment and investigations that are already available in routine practice, within roughly eighteen months of data collection. Topics that depend on external funding, specialised assays, multicentre coordination or long follow-up tend to stall. Choosing a condition the department already sees in volume matters more than choosing a novel one.

Can a thesis be published as a research paper afterwards?

Yes, and it is generally expected. A thesis is usually condensed into a paper of around three to four thousand words, restructured into the standard introduction, methods, results and discussion format, with the review of literature shortened considerably. Journals differ in their requirements, and the ethics approval number from the original thesis is normally cited in the methods section.

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