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Medical Thesis Topics

DrNB · FNB

50 Paediatric Haematology and Oncology Thesis Topics

Academic session 2026-2027  · 50 topics

This page lists 50 paediatric haematology and oncology thesis topics for DrNB and FNB candidates in India for the 2026-2027 academic session. Two features shape research here: treatment abandonment is a major determinant of outcome in Indian practice and is entirely researchable, and thalassaemia and other haemoglobinopathies form a large transfusion dependent population that attends regularly.

The paediatric haematology and oncology thesis topics below cover acute leukaemia and its treatment course, lymphoma and paediatric solid tumours, thalassaemia and haemoglobinopathies, bleeding and coagulation disorders, bone marrow failure, supportive care and febrile neutropenia, treatment abandonment, and the family and quality of life dimensions of childhood cancer.

Click any topic to open it in the protocol generator with the title already filled in.

  1. A cross-sectional study of the clinical and haematological profile of children with acute lymphoblastic leukaemiaGet protocol
  2. An observational study of the immunophenotypic profile of childhood acute leukaemiaGet protocol
  3. A study of the response to induction therapy in children with acute lymphoblastic leukaemiaGet protocol
  4. An observational study of induction related mortality and its determinants in childhood leukaemiaGet protocol
  5. A cross-sectional study of the clinical profile of children with acute myeloid leukaemiaGet protocol
  6. A study of minimal residual disease assessment and its correlates in childhood leukaemiaGet protocol
  7. An observational study of the toxicity encountered during maintenance therapy in childhood leukaemiaGet protocol
  8. A cross-sectional study of central nervous system involvement at diagnosis in childhood leukaemiaGet protocol
  9. A cross-sectional study of the clinicopathological profile of children with lymphomaGet protocol
  10. An observational study of the stage at presentation and treatment pattern in paediatric lymphomaGet protocol
  11. A study of the clinical spectrum of paediatric solid tumours at a tertiary care centreGet protocol
  12. An observational study of the presentation and staging of children with neuroblastomaGet protocol
  13. A cross-sectional study of the clinical profile of children with renal tumoursGet protocol
  14. An observational study of the presentation and management of children with bone tumoursGet protocol
  15. A study of the age at diagnosis and duration of symptoms before presentation in childhood cancerGet protocol
  16. A cross-sectional study of the clinical and haematological profile of children with thalassaemia majorGet protocol
  17. An observational study of transfusion requirement and its determinants in transfusion dependent childrenGet protocol
  18. A study of iron overload assessed by serum ferritin and imaging in multiply transfused childrenGet protocol
  19. An observational study of chelation therapy adherence and its determinants among children with thalassaemiaGet protocol
  20. A cross-sectional study of endocrine and cardiac complications in children with thalassaemiaGet protocol
  21. A study of growth and nutritional status among children with transfusion dependent thalassaemiaGet protocol
  22. An observational study of red cell alloimmunisation among multiply transfused childrenGet protocol
  23. A cross-sectional study of quality of life among children with thalassaemia assessed by a validated instrumentGet protocol
  24. A study of the carrier screening yield among family members of children with haemoglobinopathyGet protocol
  25. A cross-sectional study of the clinical profile of children with sickle cell diseaseGet protocol
  26. An observational study of the frequency and precipitants of vaso-occlusive crisis in childrenGet protocol
  27. A study of hydroxyurea use and its clinical effect in children with sickle cell diseaseGet protocol
  28. A cross-sectional study of the aetiological profile of anaemia among children referred to a haematology serviceGet protocol
  29. An observational study of the clinical and laboratory profile of children with immune thrombocytopeniaGet protocol
  30. A study of treatment response in children with newly diagnosed immune thrombocytopeniaGet protocol
  31. A cross-sectional study of the clinical profile and management of children with haemophiliaGet protocol
  32. An observational study of joint status and functional limitation in children with severe haemophiliaGet protocol
  33. A study of inhibitor development among children receiving factor replacement therapyGet protocol
  34. A cross-sectional study of the evaluation of children presenting with unexplained bleedingGet protocol
  35. A cross-sectional study of the clinical profile of children with aplastic anaemiaGet protocol
  36. An observational study of bone marrow findings in children presenting with pancytopeniaGet protocol
  37. A study of the clinical spectrum of inherited bone marrow failure syndromes in childrenGet protocol
  38. A cross-sectional study of the incidence and profile of febrile neutropenia among children on chemotherapyGet protocol
  39. An observational study of the microbiological profile of infection in neutropenic childrenGet protocol
  40. A study of the outcome and predictors of mortality in children admitted with febrile neutropeniaGet protocol
  41. An observational study of mucositis severity and its management in children receiving chemotherapyGet protocol
  42. A cross-sectional study of nutritional status and its change during cancer treatment in childrenGet protocol
  43. A study of transfusion requirement among children undergoing cancer treatmentGet protocol
  44. An observational study of chemotherapy induced nausea and vomiting control in childrenGet protocol
  45. A cross-sectional study of treatment abandonment and its determinants in childhood cancerGet protocol
  46. An observational study of the distance travelled by families and its association with treatment completionGet protocol
  47. A study of the out of pocket expenditure incurred by families of children with cancerGet protocol
  48. A cross-sectional study of parental understanding of diagnosis and treatment intent in childhood cancerGet protocol
  49. An observational study of psychological distress among parents of children undergoing cancer treatmentGet protocol
  50. A study of school attendance and reintegration among children completing cancer treatmentGet protocol

Choosing a Paediatric Haematology and Oncology thesis topic

Why is treatment abandonment studied so often in Indian paediatric oncology?

Because it determines outcome more than disease biology does in many Indian centres, and unlike biology it is modifiable. Abandonment is driven by cost, distance from the treating centre, family circumstance and understanding of curability. Documenting its frequency and determinants produces findings that a hospital can act on, which is why it recurs in theses from this specialty.

What outcomes fit a paediatric oncology thesis?

Induction response and remission status, toxicity graded during treatment, febrile neutropenia episodes and their outcome, treatment interruption and dose intensity delivered, nutritional status during therapy, and abandonment. Event free and overall survival need years of follow-up and a stable cohort, neither of which a three year programme can provide.

What sample size is realistic in paediatric haematology and oncology?

Thalassaemia clinics often follow one to three hundred children who attend regularly, which makes that population unusually accessible. Acute leukaemia accrues at perhaps two to five new cases a month even at referral centres, and solid tumours more slowly still, so studies in those areas should cover every child registered during the period rather than aim at a fixed target.

Thesis and protocol questions

How is a thesis topic different from a thesis protocol?

The topic is the title — the question a study sets out to answer, together with the population and the design. The protocol is the full document built around it: background, review of literature, aims and objectives, inclusion and exclusion criteria, sample size calculation, methodology, statistical plan, ethics considerations, consent documents and references. A topic is agreed with a guide first; the protocol is written afterwards and submitted to the institutional ethics committee.

When does a postgraduate thesis have to be submitted?

For most Indian postgraduate programmes the protocol is submitted within the first six months of joining, and the completed thesis is submitted at least six months before the final examination. Exact deadlines are set by the university, so the departmental circular for the current session takes precedence over any general timeline.

How is sample size decided for a postgraduate thesis?

Sample size follows from the primary objective, not the other way round. A prevalence study is powered from an expected proportion and an acceptable margin of error; a comparative study is powered from the expected difference between groups, the standard deviation, alpha and desired power. The figure should then be checked against the institution's actual case load for the study period, because a statistically ideal sample that cannot be recruited in the time available is not a workable plan.

Does a thesis topic need ethics committee approval?

Yes. Every postgraduate thesis involving human participants, human data or human samples requires clearance from the institutional ethics committee before data collection begins. Approval is granted on the protocol rather than on the title, and the submission usually includes the protocol, the participant information sheet and the consent form in English and in the local language.

What makes a topic realistic for a three-year postgraduate programme?

A workable topic can be completed at a single centre, with equipment and investigations that are already available in routine practice, within roughly eighteen months of data collection. Topics that depend on external funding, specialised assays, multicentre coordination or long follow-up tend to stall. Choosing a condition the department already sees in volume matters more than choosing a novel one.

Can a thesis be published as a research paper afterwards?

Yes, and it is generally expected. A thesis is usually condensed into a paper of around three to four thousand words, restructured into the standard introduction, methods, results and discussion format, with the review of literature shortened considerably. Journals differ in their requirements, and the ethics approval number from the original thesis is normally cited in the methods section.

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