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Medical Thesis Topics

MD · DNB

50 Palliative Medicine Thesis Topics

Academic session 2026-2027  · 50 topics

This page lists 50 palliative medicine thesis topics for MD and DNB candidates in India for the 2026-2027 academic session. Palliative research is measured almost entirely through what the patient reports, which makes validated symptom and quality of life instruments the foundation of any workable design, and makes the assessment burden itself an ethical consideration.

The palliative medicine thesis topics below reflect that. They cover symptom burden and assessment, cancer pain and opioid use, breathlessness and other physical symptoms, psychological distress, quality of life, caregiver burden, communication and awareness of prognosis, home based palliative care, non-cancer palliative need and end of life care.

Click any topic to open it in the protocol generator with the title already filled in.

  1. A cross-sectional study of symptom burden assessed by a validated instrument among patients referred for palliative careGet protocol
  2. An observational study of the pattern and severity of symptoms in patients with advanced malignancyGet protocol
  3. A study of the change in symptom scores following palliative care intervention over a defined periodGet protocol
  4. A comparative study of symptom burden between patients with advanced cancer and advanced non-malignant diseaseGet protocol
  5. A cross-sectional study of the concordance between patient reported and clinician assessed symptom severityGet protocol
  6. A cross-sectional study of pain prevalence and severity among patients with advanced malignancyGet protocol
  7. An observational study of pain relief following the initiation of a stepped analgesic regimenGet protocol
  8. A study of breakthrough pain and its management in patients receiving palliative careGet protocol
  9. A cross-sectional study of neuropathic pain and its characteristics in patients with advanced cancerGet protocol
  10. An observational study of opioid prescribing patterns in a palliative care serviceGet protocol
  11. A study of barriers to opioid access reported by patients and clinicians in a palliative settingGet protocol
  12. A cross-sectional study of opioid related adverse effects and their managementGet protocol
  13. A cross-sectional study of breathlessness and its severity in patients with advanced diseaseGet protocol
  14. An observational study of the management and response of refractory breathlessness in palliative patientsGet protocol
  15. A study of fatigue and its determinants among patients receiving palliative careGet protocol
  16. A cross-sectional study of nausea and vomiting and their management in advanced malignancyGet protocol
  17. An observational study of constipation and its management in patients receiving opioid therapyGet protocol
  18. A study of oral symptoms and their impact on nutrition in patients with advanced diseaseGet protocol
  19. A cross-sectional study of nutritional status and appetite among patients referred for palliative careGet protocol
  20. An observational study of pressure ulcer risk and occurrence among patients with advanced illnessGet protocol
  21. A cross-sectional study of anxiety and depression assessed by a validated scale in patients with advanced diseaseGet protocol
  22. An observational study of psychological distress and its determinants among palliative care patientsGet protocol
  23. A study of demoralisation and hopelessness among patients with advanced malignancyGet protocol
  24. A cross-sectional study of spiritual concerns reported by patients receiving palliative careGet protocol
  25. An observational study of the association between symptom burden and psychological distressGet protocol
  26. A cross-sectional study of quality of life assessed by a validated instrument in patients with advanced malignancyGet protocol
  27. An observational study of the determinants of quality of life among patients receiving palliative careGet protocol
  28. A study of the change in quality of life following referral to a palliative care serviceGet protocol
  29. A comparative study of quality of life between patients receiving home based and hospital based palliative careGet protocol
  30. A cross-sectional study of caregiver burden assessed by a validated interview among family caregiversGet protocol
  31. An observational study of the determinants of caregiver burden in advanced illnessGet protocol
  32. A study of psychological distress among caregivers of patients receiving palliative careGet protocol
  33. A cross-sectional study of the unmet needs reported by family caregivers of patients with advanced diseaseGet protocol
  34. An observational study of caregiver understanding of the patient’s condition and treatment planGet protocol
  35. A cross-sectional study of patient awareness of diagnosis and prognosis in advanced malignancyGet protocol
  36. An observational study of communication preferences among patients receiving palliative careGet protocol
  37. A study of the concordance between patient and family preferences regarding disclosure of prognosisGet protocol
  38. A cross-sectional study of advance care planning discussions in a palliative care serviceGet protocol
  39. An observational study of documented preferences regarding place of care and place of deathGet protocol
  40. A cross-sectional study of the profile of patients enrolled in a home based palliative care programmeGet protocol
  41. An observational study of the frequency and content of home visits in a palliative care serviceGet protocol
  42. A study of emergency department attendance among patients enrolled in home based palliative careGet protocol
  43. A comparative study of symptom control between patients receiving home based and clinic based careGet protocol
  44. A cross-sectional study of the palliative care needs of patients with advanced non-malignant diseaseGet protocol
  45. An observational study of the referral pattern and timing of palliative care referralGet protocol
  46. A study of the palliative care needs of patients with end stage organ failureGet protocol
  47. A cross-sectional study of the profile and needs of children referred for palliative careGet protocol
  48. An observational study of the care received by patients in the last week of lifeGet protocol
  49. A study of place of death and its determinants among patients receiving palliative careGet protocol
  50. A cross-sectional study of knowledge and attitude regarding palliative care among clinical staffGet protocol

Choosing a Palliative Medicine thesis topic

What ethical issues are specific to palliative research?

Vulnerability and burden. Participants are seriously ill, often fatigued, and may feel unable to decline a request from the team treating them. The protocol should state that participation is voluntary and will not affect care, keep the assessment short, allow it to be stopped at any point, and describe what happens if a participant deteriorates or dies during the study. Committees look for all of these explicitly.

Which instruments are used in palliative medicine research?

Established patient-reported tools rather than clinician impression. The Edmonton Symptom Assessment System for symptom burden, the Brief Pain Inventory or a numerical rating scale for pain, the European Organisation for Research and Treatment of Cancer quality of life questionnaire, the Hospital Anxiety and Depression Scale, and the Zarit Burden Interview for caregivers are all widely used. Confirm an Indian language version exists before recruiting.

Can prognosis or survival be studied in a palliative thesis?

With care. Prognostic scores can be applied at enrolment and their accuracy assessed against subsequent outcome, and that is a legitimate and common design. But it means recording deaths, which requires a clear plan for how families will be contacted and how that contact will be handled sensitively. Many candidates find cross-sectional symptom and quality of life work a more manageable choice for a first protocol.

Thesis and protocol questions

How is a thesis topic different from a thesis protocol?

The topic is the title — the question a study sets out to answer, together with the population and the design. The protocol is the full document built around it: background, review of literature, aims and objectives, inclusion and exclusion criteria, sample size calculation, methodology, statistical plan, ethics considerations, consent documents and references. A topic is agreed with a guide first; the protocol is written afterwards and submitted to the institutional ethics committee.

When does a postgraduate thesis have to be submitted?

For most Indian postgraduate programmes the protocol is submitted within the first six months of joining, and the completed thesis is submitted at least six months before the final examination. Exact deadlines are set by the university, so the departmental circular for the current session takes precedence over any general timeline.

How is sample size decided for a postgraduate thesis?

Sample size follows from the primary objective, not the other way round. A prevalence study is powered from an expected proportion and an acceptable margin of error; a comparative study is powered from the expected difference between groups, the standard deviation, alpha and desired power. The figure should then be checked against the institution's actual case load for the study period, because a statistically ideal sample that cannot be recruited in the time available is not a workable plan.

Does a thesis topic need ethics committee approval?

Yes. Every postgraduate thesis involving human participants, human data or human samples requires clearance from the institutional ethics committee before data collection begins. Approval is granted on the protocol rather than on the title, and the submission usually includes the protocol, the participant information sheet and the consent form in English and in the local language.

What makes a topic realistic for a three-year postgraduate programme?

A workable topic can be completed at a single centre, with equipment and investigations that are already available in routine practice, within roughly eighteen months of data collection. Topics that depend on external funding, specialised assays, multicentre coordination or long follow-up tend to stall. Choosing a condition the department already sees in volume matters more than choosing a novel one.

Can a thesis be published as a research paper afterwards?

Yes, and it is generally expected. A thesis is usually condensed into a paper of around three to four thousand words, restructured into the standard introduction, methods, results and discussion format, with the review of literature shortened considerably. Journals differ in their requirements, and the ethics approval number from the original thesis is normally cited in the methods section.

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