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Medical Thesis Topics

FNB · DrNB · PDCC

30 HIV Medicine Thesis Topics

Academic session 2026-2027  · 30 topics

This page lists 30 HIV medicine thesis topics for FNB, DrNB and PDCC candidates in India for the 2026-2027 academic session. Research in this specialty concentrates on what happens to patients on long-term antiretroviral therapy rather than on the disease itself, since treatment eligibility is now universal and the questions that remain are about adherence, toxicity, comorbidity and the complications of immune reconstitution.

The HIV medicine thesis topics below are built on that clinical agenda. They cover antiretroviral therapy outcomes, adherence determinants, drug resistance patterns, opportunistic infection profile, immune reconstitution, metabolic complications of therapy, and the comorbidities that dominate the care of patients living with human immunodeficiency virus infection on long-term treatment. A note on abbreviation: topics on this page spell out the condition in full rather than using an abbreviation.

Click any topic to open it in the protocol generator with the title already filled in.

  1. A cross-sectional study of the clinical and immunological profile of patients newly registered for antiretroviral therapyGet protocol
  2. An observational study of the virological suppression rate at six months and one year after starting antiretroviral therapyGet protocol
  3. A study of antiretroviral therapy adherence assessed by a validated method and its clinical determinantsGet protocol
  4. An observational study of treatment failure and its virological and clinical determinantsGet protocol
  5. A cross-sectional study of the drug resistance mutation pattern among patients with virological failureGet protocol
  6. An observational study of the second-line antiretroviral therapy outcome in patients with first-line failureGet protocol
  7. A study of immune reconstitution inflammatory syndrome and its clinical profileGet protocol
  8. An observational study of the pattern of opportunistic infections at the time of antiretroviral therapy initiationGet protocol
  9. A cross-sectional study of tuberculosis coinfection and its management in patients on antiretroviral therapyGet protocol
  10. An observational study of the outcome of concurrent tuberculosis and antiretroviral therapyGet protocol
  11. A cross-sectional study of the cryptococcal disease profile and management in advanced immunodeficiencyGet protocol
  12. An observational study of the clinical spectrum of central nervous system opportunistic diseaseGet protocol
  13. A study of the metabolic complications of antiretroviral therapy at one yearGet protocol
  14. An observational study of dyslipidaemia and its determinants in patients on long-term antiretroviral therapyGet protocol
  15. A cross-sectional study of cardiovascular risk factor prevalence among patients on antiretroviral therapyGet protocol
  16. An observational study of renal function and its change over time in patients on antiretroviral therapyGet protocol
  17. A study of bone mineral density and its clinical associations in patients on antiretroviral therapyGet protocol
  18. An observational study of anaemia prevalence and its determinants in patients with human immunodeficiency virus infectionGet protocol
  19. A cross-sectional study of the neuropsychological profile of patients on antiretroviral therapyGet protocol
  20. An observational study of depression and anxiety in patients living with human immunodeficiency virus infectionGet protocol
  21. A study of quality of life assessed by a validated instrument in patients on antiretroviral therapyGet protocol
  22. An observational study of nutritional status and its clinical correlates in patients on antiretroviral therapyGet protocol
  23. A cross-sectional study of the clinical profile and treatment outcome of human immunodeficiency virus infection in childrenGet protocol
  24. An observational study of growth and neurodevelopmental outcome in children on antiretroviral therapyGet protocol
  25. A study of retention in care and its determinants in patients registered for antiretroviral therapyGet protocol
  26. An observational study of loss to follow-up and its clinical and social determinantsGet protocol
  27. A cross-sectional study of the disclosure status and its clinical and psychosocial associationsGet protocol
  28. An observational study of the knowledge of transmission and prevention among patients on antiretroviral therapyGet protocol
  29. A study of the clinical profile of elderly patients living with human immunodeficiency virus infectionGet protocol
  30. An observational study of the pattern of comorbidity in patients on long-term antiretroviral therapyGet protocol

Choosing a HIV Medicine thesis topic

What makes HIV medicine research distinct from infectious disease?

Longitudinal depth. An HIV medicine service follows the same patients for years, which makes change over time measurable in a way an infectious disease consultation service cannot. Viral load trajectory, resistance mutation accumulation, metabolic change and immune reconstitution are all longitudinal outcomes requiring a cohort that only a dedicated service maintains.

What ethical and confidentiality issues apply?

Diagnosis with human immunodeficiency virus infection carries significant social consequences in India, and research data must be stored with particular attention to de-identification. Participants should be explicitly informed that their records will not be shared with family members, employers or authorities without consent. Committees examine this carefully.

What sample size is realistic?

An active human immunodeficiency virus medicine programme following several hundred patients can support two to three hundred participants for most cross-sectional and longitudinal designs. Subgroup studies — drug resistance, immune reconstitution inflammatory syndrome, specific opportunistic infections — are smaller and should cover every eligible case in the cohort.

Thesis and protocol questions

How is a thesis topic different from a thesis protocol?

The topic is the title — the question a study sets out to answer, together with the population and the design. The protocol is the full document built around it: background, review of literature, aims and objectives, inclusion and exclusion criteria, sample size calculation, methodology, statistical plan, ethics considerations, consent documents and references. A topic is agreed with a guide first; the protocol is written afterwards and submitted to the institutional ethics committee.

When does a postgraduate thesis have to be submitted?

For most Indian postgraduate programmes the protocol is submitted within the first six months of joining, and the completed thesis is submitted at least six months before the final examination. Exact deadlines are set by the university, so the departmental circular for the current session takes precedence over any general timeline.

How is sample size decided for a postgraduate thesis?

Sample size follows from the primary objective, not the other way round. A prevalence study is powered from an expected proportion and an acceptable margin of error; a comparative study is powered from the expected difference between groups, the standard deviation, alpha and desired power. The figure should then be checked against the institution's actual case load for the study period, because a statistically ideal sample that cannot be recruited in the time available is not a workable plan.

Does a thesis topic need ethics committee approval?

Yes. Every postgraduate thesis involving human participants, human data or human samples requires clearance from the institutional ethics committee before data collection begins. Approval is granted on the protocol rather than on the title, and the submission usually includes the protocol, the participant information sheet and the consent form in English and in the local language.

What makes a topic realistic for a three-year postgraduate programme?

A workable topic can be completed at a single centre, with equipment and investigations that are already available in routine practice, within roughly eighteen months of data collection. Topics that depend on external funding, specialised assays, multicentre coordination or long follow-up tend to stall. Choosing a condition the department already sees in volume matters more than choosing a novel one.

Can a thesis be published as a research paper afterwards?

Yes, and it is generally expected. A thesis is usually condensed into a paper of around three to four thousand words, restructured into the standard introduction, methods, results and discussion format, with the review of literature shortened considerably. Journals differ in their requirements, and the ethics approval number from the original thesis is normally cited in the methods section.

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