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Medical Thesis Topics

DM · DrNB

50 DM Infectious Disease Thesis Topics

Academic session 2026-2027  · 50 topics

This page lists 50 infectious disease thesis topics for DM and DrNB candidates in India for the 2026-2027 academic session. The superspecialty differs from microbiology in where it stands: microbiology studies the organism, infectious disease studies the patient and the decision, and a thesis should reflect that distinction rather than duplicate the laboratory’s work.

The infectious disease thesis topics below focus on clinical management. They cover antimicrobial stewardship and prescribing appropriateness, resistant organism infections and their outcomes, sepsis and bloodstream infection, healthcare associated infection, infection in immunocompromised and transplant patients, human immunodeficiency virus medicine, and infection prevention practice.

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  1. A cross-sectional point prevalence study of antimicrobial use in a tertiary care hospitalGet protocol
  2. An audit of the appropriateness of empirical antimicrobial therapy against institutional guidelinesGet protocol
  3. An observational study of antimicrobial de-escalation following culture and susceptibility resultsGet protocol
  4. A study of the duration of antimicrobial therapy and its concordance with recommended practiceGet protocol
  5. A comparative study of antimicrobial prescribing before and after a stewardship interventionGet protocol
  6. A cross-sectional study of the utilisation of reserve antimicrobials and its justificationGet protocol
  7. An observational study of antimicrobial consumption measured by defined daily dose across departmentsGet protocol
  8. A study of the appropriateness of surgical antimicrobial prophylaxis duration and choiceGet protocol
  9. A cross-sectional study of the clinical profile and outcome of infections caused by carbapenem resistant organismsGet protocol
  10. An observational study of risk factors for infection with multidrug resistant organismsGet protocol
  11. A study of the outcome of patients treated with colistin for resistant gram negative infectionGet protocol
  12. A comparative study of clinical outcome between infections with sensitive and resistant organismsGet protocol
  13. An observational study of the clinical profile of patients with methicillin resistant staphylococcal infectionGet protocol
  14. A cross-sectional study of the clinical profile and outcome of patients admitted with sepsisGet protocol
  15. An observational study of the time to appropriate antimicrobial therapy and its association with outcomeGet protocol
  16. Evaluation of a validated severity score for predicting mortality in patients with bloodstream infectionGet protocol
  17. A study of the aetiology and outcome of community acquired bloodstream infectionGet protocol
  18. An observational study of serum lactate clearance and its association with outcome in sepsisGet protocol
  19. A study of source control adequacy and its influence on outcome in severe infectionGet protocol
  20. A cross-sectional study of the incidence and profile of healthcare associated infectionsGet protocol
  21. An observational study of central line associated bloodstream infection and its determinantsGet protocol
  22. A study of catheter associated urinary tract infection and its preventive practiceGet protocol
  23. An observational study of ventilator associated pneumonia and its clinical profileGet protocol
  24. A cross-sectional study of hand hygiene compliance and its variation across professional categoriesGet protocol
  25. An audit of infection prevention practices in a critical care area against defined standardsGet protocol
  26. A study of surgical site infection following clean and clean contaminated proceduresGet protocol
  27. A cross-sectional study of the clinical profile and outcome of infections in transplant recipientsGet protocol
  28. An observational study of the timing and aetiology of infection following solid organ transplantationGet protocol
  29. A study of infections in patients receiving immunosuppressive therapy for autoimmune diseaseGet protocol
  30. An observational study of invasive fungal infection in immunocompromised patientsGet protocol
  31. A cross-sectional study of the clinical spectrum of opportunistic infections in patients with advanced immunodeficiencyGet protocol
  32. A study of febrile neutropenia and its microbiological profile in haematology patientsGet protocol
  33. A cross-sectional study of the clinical and immunological profile of patients with human immunodeficiency virus infectionGet protocol
  34. An observational study of antiretroviral therapy adherence and its determinantsGet protocol
  35. A study of immune reconstitution and its clinical correlates following antiretroviral therapy initiationGet protocol
  36. An observational study of the pattern of opportunistic infections at presentation in advanced diseaseGet protocol
  37. A cross-sectional study of comorbidity and metabolic complications among patients on long term antiretroviral therapyGet protocol
  38. A study of treatment failure and its determinants among patients on antiretroviral therapyGet protocol
  39. A cross-sectional study of the diagnostic pathway followed in adults with acute undifferentiated febrile illness referred to an infectious disease serviceGet protocol
  40. An observational study of the clinical approach and diagnostic yield in pyrexia of unknown originGet protocol
  41. A study of the clinical spectrum and outcome of patients with infective endocarditisGet protocol
  42. An observational study of the aetiology and outcome of central nervous system infection in adultsGet protocol
  43. A cross-sectional study of the clinical profile of patients with bone and joint infectionGet protocol
  44. A study of the clinical spectrum and management of skin and soft tissue infectionGet protocol
  45. An observational study of the clinical profile and outcome of patients with intra-abdominal infectionGet protocol
  46. A cross-sectional study of vaccination status among adults with chronic disease attending an outpatient clinicGet protocol
  47. An observational study of post exposure prophylaxis practice following occupational exposureGet protocol
  48. A study of prescriber confidence and decision making when de-escalating antimicrobial therapyGet protocol
  49. A cross-sectional study of infection control knowledge among clinicians in a critical care areaGet protocol
  50. An observational study of the referral pattern and diagnostic spectrum in an infectious disease consultation serviceGet protocol

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Choosing a DM Infectious Disease thesis topic

How does an infectious disease thesis differ from a microbiology one?

By the unit of analysis. Microbiology counts isolates and reports susceptibility patterns; infectious disease follows patients and studies whether the treatment decision was appropriate and what happened as a result. A susceptibility surveillance study belongs in microbiology. A study of whether therapy was de-escalated after culture results, and with what outcome, belongs here.

What is an antimicrobial stewardship study and how is it designed?

It measures prescribing against a defined standard and, where possible, the effect of an intervention. Point prevalence surveys of antimicrobial use, appropriateness audits against institutional or national guidance, defined daily dose analysis, and before and after evaluation of a stewardship intervention are all established designs. Name the guideline you are auditing against, since an audit without a benchmark is only a description.

What outcomes are realistic in an infectious disease thesis?

In-hospital mortality, length of stay, clinical cure at a defined day, time to defervescence, time to appropriate therapy, de-escalation rate and readmission within thirty days. All occur inside the admission or shortly after. Longer questions such as resistance emergence over years or recurrence at twelve months are out of reach in a residency.

Thesis and protocol questions

How is a thesis topic different from a thesis protocol?

The topic is the title — the question a study sets out to answer, together with the population and the design. The protocol is the full document built around it: background, review of literature, aims and objectives, inclusion and exclusion criteria, sample size calculation, methodology, statistical plan, ethics considerations, consent documents and references. A topic is agreed with a guide first; the protocol is written afterwards and submitted to the institutional ethics committee.

When does a postgraduate thesis have to be submitted?

For most Indian postgraduate programmes the protocol is submitted within the first six months of joining, and the completed thesis is submitted at least six months before the final examination. Exact deadlines are set by the university, so the departmental circular for the current session takes precedence over any general timeline.

How is sample size decided for a postgraduate thesis?

Sample size follows from the primary objective, not the other way round. A prevalence study is powered from an expected proportion and an acceptable margin of error; a comparative study is powered from the expected difference between groups, the standard deviation, alpha and desired power. The figure should then be checked against the institution's actual case load for the study period, because a statistically ideal sample that cannot be recruited in the time available is not a workable plan.

Does a thesis topic need ethics committee approval?

Yes. Every postgraduate thesis involving human participants, human data or human samples requires clearance from the institutional ethics committee before data collection begins. Approval is granted on the protocol rather than on the title, and the submission usually includes the protocol, the participant information sheet and the consent form in English and in the local language.

What makes a topic realistic for a three-year postgraduate programme?

A workable topic can be completed at a single centre, with equipment and investigations that are already available in routine practice, within roughly eighteen months of data collection. Topics that depend on external funding, specialised assays, multicentre coordination or long follow-up tend to stall. Choosing a condition the department already sees in volume matters more than choosing a novel one.

Can a thesis be published as a research paper afterwards?

Yes, and it is generally expected. A thesis is usually condensed into a paper of around three to four thousand words, restructured into the standard introduction, methods, results and discussion format, with the review of literature shortened considerably. Journals differ in their requirements, and the ethics approval number from the original thesis is normally cited in the methods section.

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